Nucleotide Kinase of Bacteriophage T 7 1 Characterization of a Nucleotide Kinase Encoded by Bacteriophage T 7

نویسندگان

  • Ngoc Q. Tran
  • Stanley Tabor
  • Chitra J. Amarasiriwardena
  • Arkadiusz W. Kulczyk
  • Charles C. Richardson
چکیده

Background: Gene 1.7 of bacteriophagephage T7 encodes a nucleotide kinase Results: Gp1.7 dodecamers catalyze the reversible dTMP and dGMP kinase reactions Conclusion: Gp1.7 is a unique nucleotide kinase that does not require a divalent metal ion Significance: The unique nucleotide kinase of bacteriophage T7 supplies dTDP and dGDP for conversion to the nucleoside 5’-triphosphate and recycles the dTDP derived from helicase function to dTTP.

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تاریخ انتشار 2012